博士生导师
覃礼堂 教授
  1. 作者:bwin必赢
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联系方式:0773-2537332

Email:qinsar@glut.edu.cn

一、基本情况

覃礼堂,男,博士(后),教授,博士生导师。2001年同济大学环境科学专业博士学位,2013年同济大学化学系博士后出站。2013年7月至今在桂林理工大学从事教学与科研工作,2016年10月-2017年10月在丹麦哥本哈根大学做访问学者。主持国家自然科学基金、国家重点研发计划子课题和广西自然科学基金等10余个科研项目,在《Environmental Pollution》、《Science of the Total Environment》和《Chemosphere》等国内外刊物上发表SCI收录论文40余篇,申请专利10余项,获得计算机应用软件著作权2项。

二、研究方向

(1)生态与健康风险评估

(2)环境毒理学、计算毒理学

三、科研项目

1. 国家自然科学基金——基于结构-活性关系的长期低剂量唑类杀菌剂混合物毒性和相互作用定量预测研究(项目批准号21866010;起止时间2019-2022年)

2. 国家自然科学基金——S-型和J-型浓度-效应关系混合物毒性定量预测研究(项目批准号21407032;起止时间2015-2017年)

3. 国家重点研发计划子课题——喀斯特水资源生态调控技术集成与优化示(项目批准号2019YFC0507504,起止时间2019-2022)。

4. 广西科技重大专项子课题——喀斯特峰丛洼地水景观资源可持续利用调控示范(项目批准号桂科AA2016100403-03,起止时间2020-2023)。

5. 广西自然科学基金——整合生物毒性与化学结构信息预测低剂量农药和PPCPs混合物协同作用(项目批准号2017GXNSFAA198346;起止时间2017-2020年)

6. 广西自然科学基金——农药混合污染物对青海弧菌Q67的联合毒性作用机理(项目批准号2014GXNSFBA118233;起止时间2014-2017年)

7. 桂林市科学技术研究开发项目——桂林市会仙湿地高风险农药复合污染水生态修复技术研究(项目批准号2016012505;起止时间2016-2018年)

8. 桂林市科学技术研究开发项目——城市河流湿地中抗生素的污染特征及生态毒性研究(项目批准号20180107-5,起止时间2019-2021年)

9. 广西高校科学技术研究项目——典型PPCPs混合污染物联合毒性及预测模型研究(项目批准号ZD2014059,起止时间2014-2016)

10. 中国博士后科学基金——水溶性混合污染物的分子结构表征及定量-构效关系研究(项目批准号2012M520932,起止时间2012-2013年)

四、主要成果

(一)期刊论文

1. 刘洁雪,梁萧,覃礼堂*,莫凌云,梁延鹏,曾鸿鹄,袁星义.漓江流域有机磷农药和磺胺类抗生素的复合污染及其生态风险.环境科学研究. 2022, 35(1):60-69.

2. Lingyun Mo,Baikang Yuan, Jie Zhu,Litang Qin*, Junfeng Dai*.QSAR models for predicting additive and synergistic toxicities of binary pesticide mixtures onScenedesmus Obliquus.Chinese Journal of Structural Chemistry. https://doi.org/10.14102/j.cnki.0254-5861.2011-3306

3. Qiongyuan Nong, Yongan Liu,Litang Qin*, Min Liu, Lingyun Mo, Yanpeng Liang, Honghu Zeng. Toxic mechanism of three azole fungicides and their mixture to green alga Chlorella pyrenoidosa[J]. Chemosphere, 2021, 262:127793.

4. Litang Qin, Min Liu, Xin Zhang, Lingyun Mo*, Honghu Zeng, Yanpeng Liang.Concentration Addition, Independent Action, and QSAR for Chemical Mixture Toxicities of the Disinfection Byproducts of Haloacetic Acids on the Green AlgaRaphidocelis subcapitata. Environmental Toxicology and Chemistry.2021, 40(5): 1431–1442.

5. 刘敏,覃礼堂*,莫凌云,梁延鹏,曾鸿鹄. 4种唑类杀菌剂对蛋白核小球藻的急性毒性及其致毒机理研究.生态毒理学报,2021,16(4): 301-312.

6. Lingyun Mo, Yongan Liu, Jie Zhu,Litang Qin*, Yanpeng Liang*, Honghu Zeng. Benefits from hazards, benefits from nothing, and benefits from benefits: the combined effects of five quaternary ammonium compounds to Vibrio qinghaiensis Q67. Environ Sci Eur,2020, 32: 35.

7. Lingyun Mo, Wen Ma, Song Kong,Litang Qin*, Yanpeng Liang, Junfeng Dai*, Shushen Liu, Study of the Binding Mode of Quaternary ammonium cationic surfactant to firefly luciferase and the prediction of binary mixture toxicity. Chinese Journal of Structural Chemistry.2020, 39(6): 1167-1177.

8. Litang Qin, Xinrui Pang, Hongru Zeng, Yanpeng Liang*, Lingyun Mo,Dunqiu Wang, Junfeng Dai*. Ecological and human health risk of sulfonamides in surface water and groundwater of Huixian karst wetland in Guilin, China, Science of the Total Environment,2020, 708:134552.

9. 农琼媛,覃礼堂*,莫凌云,刘勇安,梁延鹏.抗生素与三唑类杀菌剂混合物对羊角月牙藻的长期毒性相互作用研究.生态毒理学报,2019, 14(4): 140-149.

10. Yuhan Chen,Litang Qin*, Lingyun Mo, Danna Zhao, Honghu Zeng, Yanpeng Liang. Synergetic effects of novel aromatic brominated and chlorinated disinfection byproducts on Vibrio qinghaiensis sp.-Q67. Environmental Pollution, 2019, 250: 375-385.(SCI)

11. Litang Qin, Xin Zhang, Yuhan Chen, Lingyun Mo*, Honghu Zeng, Yanpeng Liang, Hua Lin*, Dunqiu Wang. Predicting the cytotoxicity of disinfection by-products to Chinese hamster ovary by using linear quantitative structure–activity relationship models. Environmental Science and Pollution Research. 2019, 26(16) 16606–16615.(SCI)

12. Honghu Zeng, Xin Fu, Yanpeng Liang*,Litang Qin*, Lingyun Mo. Risk assessment of an organochlorine pesticide mixture in the surface waters of Qingshitan Reservoir in Southwest China. RSC Advances,2018, 8, 17797–17805.(SCI)

13. Litang Qin, Yuhan Chen, Xin Zhang, Lingyun Mo*, Honghu Zeng, Yanpeng Liang*. QSAR prediction of additive and non-additive mixture toxicities of antibiotics and pesticide. Chemosphere.2018, 198, 122-129.(SCI)

14. 莫凌云,梁丽营,覃礼堂*,秦萌,高欢欢.定性与定量评估4种重金属及2种农药混合物对费氏弧菌的毒性相互作用.生态毒理学报,2018, 13(1): 251-260.

15. Lingyun Mo, Danna Zhao, Meng Qin,Litang Qin*, Honghu Zeng, Yanpeng Liang. Joint toxicity of six common heavy metals toChlorella pyrenoidosa. Environ Sci Pollut Res,2017, 5: 1-7(SCI)

16. Litang Qin, Xin Zhang, Yuhan Chen, Lingyun Mo, Honghu Zeng, Yanpeng Liang. Predictive QSAR models for the toxicity of disinfection byproducts. Molecules,2017, 22, 1671; doi:10.3390(SCI)

17. Lingyun Mo,Litang Qin*, Jie Liu, Honghu Zeng, Yanpeng Liang. Interaction analysis of binary mixtures containing aspirin and oxytetracycline using factorial interaction method. Journal of Environmental Protection and Ecology.2017, 18(3): 913-921.(SCI)

18. 莫凌云,覃如琼,覃礼堂*,曾鸿鹄,梁延鹏.基于分子电性距离矢量预测有机磷杀虫剂的小鼠毒性.桂林理工大学学报,2017, 37(2):1-6 (中文核心)

19. Litang Qin, Xin Zhang, Lingyun Mo, Yanpeng Liang, Honghu Zeng. Further exploring linear concentration addition and independent action for predicting non-interactive mixture toxicity. Chinese J Struct Chem2017, 36(6): 886-896(SCI)

20. Lingyun Mo, Jie Liu*,Litang Qin*, Honghu Zeng, Yanpeng Liang. Two-Stage Prediction on Effects of Mixtures Containing Phenolic Compounds and Heavy Metals onVibrio qinghaiensis sp.Q67. Bull Environ Contam Toxicol,2017, 99(1): 17–22.(SCI)

21. Lingyun Mo, Minyi Zheng, Meng Qin, Xin Zhang, Jie Liu,Litang Qin*, Yanpeng Liang. Quantitative characterization of the toxicities of Cd-Ni and Cd-Cr binary mixtures using combination index method. BioMed Research International,2016, 2016: 1-6(SCI)

22. 吴洁,莫凌云,覃礼堂*,曾鸿鹄,梁延鹏,覃如琼,朱义年.部分抗生素对小鼠毒性的QSTR研究.桂林理工大学学报,2016, 36(2):349-335 (中文核心)

23. Lingyun Mo, Ruqiong Qin,Litang Qin*, Honghu Zeng, Yanpeng Liang. Study on the quantitative relationship between the structure and toxicity of organophosphorus pesticide. Chinese J. Struct. Chem.2015, 34(10): 1473-1478(SCI)

24. Litang Qin, Jie Wu, Lingyun Mo, Honghu Zeng*, Yanpeng Liang. Linear regression model for predicting interactive mixture toxicity of pesticide and ionic liquid. Environ Sci Pollut Res,2015, 22(16): 12759-12768(SCI)

25. 覃礼堂,刘树深*,莫凌云.改进的整合加和模型INFCIM及其应用于混合物毒性预测.中国环境科学,2014, 34(7): 1890-1896(EI)

26. Huanhuan Gao,Litang Qin*, Liangliang Huang, Yanpeng Liang, Lingyun Mo, Honghu Zeng. Progress on the combined effects of PPCP residues in drinking water. Advances in Energy, Environment and Materials Science.2016, 6: 97-100 (EI)

27. M. Tang, Honghu Zeng,Litang Qin*. Overview of pesticide toxicity studies on oblique Scenedesmus. Adv. Mater. Res.2014, 1010-1012: 1220-1224(EI)

28. Jie Wu, Lingyun Mo,Litang Qin, Zongqiang Zhu* , Yinian Zhu. Research advancement of the joint toxicity of heavy metals mixture. Adv. Mater. Res.2014, 522-524: 532(EI)

29. 曾鸿鹄,覃如琼,莫凌云*,覃礼堂.有机氯农药对人体健康毒性研究进展.桂林理工大学学报,2014, 34(3), 549-553 (中文核心)

30. Miao Tang, Honghu Zeng,Litang Qin*. Overview of pesticide toxicity studies on oblique Scenedesmus. Adv Mater Res2014, 1010-1012: 1220-1224.(EI)

31. 覃礼堂,刘树深*,肖乾芬,吴庆生. QSAR模型内部和外部验证方法综述.环境化学,2013, 32 (7): 1205-1211. (中文核心)

32. Litang Qin, Shushen. Liu*, Fu Chen, Qianfen Wu. Development of validated quantitative structure–retention relationship models for retention indices of plant essential oils.J Sep Sci2013, 36(9-10): 1553-1560. (SCI)

33. Litang Qin, Shushen Liu, Fu Chen, Qianfen Xiao, Qingsheng Wu. Chemometric model for predicting retention indices of constituents of essential oils.Chemosphere2013, 90(2): 300-305. (SCI)

34. Litang Qin, Shushen Liu*, Jin Zhang, Qqianfen Xiao. A novel model integrated concentration addition with independent action for the prediction of toxicity of multi-component mixture.Toxicology2011, 280(3): 164-172. (SCI)

35. Litang Qin, Shushen Liu*, Hailing Liu, Yahui Zhang.Support vector regression and least squares support vector regression for hormetic dose–response curves fitting.Chemosphere2010, 78(3): 327-334. (SCI)

36. Litang Qin, Shushen Liu*, Hailing Liu.QSPR model for bioconcentration factors of nonpolar organic compounds using molecular electronegativity distance vector descriptors.Mol Divers2010, 14(1): 67-80.(SCI).

37. Litang Qin, Shushen Liu*, Hailing Liu, Juan Tong.Comparative multiple quantitative structure-retention relationships modeling of gas chromatographic retention time of essential oils using multiple linear regression, principal component regression, and partial least squares techniques.J Chromatogr A2009, 1216(27): 5302-5312. (SCI).

38. Litang Qin, Shushen Liu*,Hailing Liu, Huilin Ge. A new predictive model for the bioconcentration factors of polychlorinated biphenyls (PCBs) based on the molecular electronegativity distance vector (MEDV).Chemosphere2008, 70(9): 1577-1587. (SCI)

39. Shushen Liu*,Litang Qin, Hailing Liu, Daqiang Yin.Molecular electronegativity distance vector model for the Prediction of bioconcentration factors in fish.J Mol Model2008, 14(2): 83-92. (SCI)

(二)专利

1. 覃礼堂,刘洁雪,莫凌云,梁延鹏,曾鸿鹄.一种基于独立作用模型的重金属复合污染风险评估方法.申请号:202110554589.X.申请日期:2021年5月21日。

2. 覃礼堂,刘洁雪,莫凌云,梁延鹏,曾鸿鹄.一种基于浓度加和模型的重金属复合污染风险评估方法.申请号:202110554601.7.申请日期:2021年5月21日。

3. 刘敏,覃礼堂,莫凌云.一种检测绿藻细胞凋亡的方法.申请号:202011134975.5.申请日期:2020年10月22日。

4. 刘敏,覃礼堂,莫凌云,梁延鹏,曾鸿鹄,宋晓红.一种污染物对绿藻细胞内活性氧含量影响的测定方法.申请号:202010815512.9,申请日期:2020年08月14日。

5. 覃礼堂,梁洧菡,曾莎莎,梁延鹏,莫凌云,曾鸿鹄.一种分离富集水环境中16种有机磷农药的方法.申请号:202010011704.4,申请日期:2020年01月06日。

6. 覃礼堂,农琼媛,莫凌云,代俊峰,曾鸿鹄.梁延鹏.一种利用混合绿藻评价单一三唑类杀菌剂农药毒性的方法,申请号:201910431926.9,申请日期:2019年05月22日。

7. 覃礼堂,农琼媛,莫凌云,代俊峰,曾鸿鹄,梁延鹏.一种预测典型抗生素与农药联合毒性相互作用的方法.申请号:201910431870.7,申请日期:2019年05月22日。

8. 覃礼堂,农琼媛,莫凌云,曾鸿鹄,梁延鹏,代俊峰.一种筛选最佳绿藻组合混合培养的方法.申请号:201910820407.1,申请日期:2019年09月01日。

(三)科研获奖

朱宗强,莫凌云,冯国杰,李淑彩,覃礼堂,张立浩,朱义年,吕正勇.土壤重金属污染修复及其安全风险防控技术开发与应用.广西科学技术发明奖二等奖,2020年.

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